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Gene Therapy for Hemophilia Studied.

The Medical College of Wisconsin received a five-year, $1.8 million grant from the National Institutes of Health’s National Heart, Lung, and Blood Institute to investigate therapies for hemophilia A. Qizhen Shi, MD, PhD, assistant professor of pediatric hematology/oncology at the Medical College, and a researcher at Children’s Hospital of Wisconsin and the BloodCenter of Wisconsin, is the principal investigator for the grant.

Alliance for Cancer Gene Therapy Welcomes Applications for Young Investigator Awards.

The Alliance for Cancer Gene Therapy, the only public charity in the United States dedicated exclusively to funding cancer gene therapy research, is accepting abstract submissions for its Fund for Discovery Young Investigators awards.

A phase I clinical trial of thymidine kinase-based gene therapy in advanced hepatocellular carcinoma.

The aim of this phase I clinical trial was to assess the feasibility and safety of intratumoral administration of a first-generation adenoviral vector encoding herpes simplex virus thymidine kinase (HSV-TK) gene (Ad.TK) followed by systemic ganciclovir to patients with advanced hepatocellular carcinoma (HCC).

A 17-year-old Cambridge biotechnology firm is betting $35 million in new financing on the success of its budding gene therapy program.

This spring, Genetix Pharmaceuticals reinvented itself as the developer of treatments for two rare and devastating genetic disorders.

Left untreated, both diseases — the blood disorder beta-thalassemia major and the brain-wasting disease Adrenoleukodystrophy, or ALD — are fatal. And existing treatments can be as dangerous as the diseases.

Liposomes for gene transfer in cancer therapy.

Gradalis Inc has developed improved liposomes that produce efficacy for the treatment of cancer, cardiovascular diseases, and HIV-1-related diseases in small and large animal models.

Georgetown U. Hospital closes lab after problems with breast cancer tests.

Georgetown University Hospital has shut down a lab that performs genetic analysis for breast cancer patients and has had 249 women's tissue samples independently retested while federal health officials investigate procedures at the lab.

Integral Molecular Announces Key Patent Issued on Lipoparticle Technology for Deriving High Concentrations of Cell-free Membrane Proteins.

PHILADELPHIA--(BUSINESS WIRE)--Integral Molecular, Inc. today announced the issuance of a key patent covering its technology for deriving high concentrations of membrane proteins.

TroVax trial on prostate cancer patients.

GENE THERAPY company Oxford Biomedica has received permission from US regulators to test its treatment on prostate cancer patients.

Is gene therapy ready for a development renaissance?

Genetix is betting $35 million in fresh financing that gene therapy is ready for a renaissance. Profiled by the Boston Globe, Genetix is using a new viral vector approach to deliver healthy replacement genes needed to check rare diseases.

Gaining the hard yard: pre-clinical evaluation of lentiviral-mediated gene therapy for the treatment of beta-thalassemia.

Gene therapy is one potential novel therapeutic avenue for the treatment of inherited monogenic disorders.

Herpes virus used to treat cancer.

Doctors say they have used a genetically engineered herpes virus to treat successfully patients with head and neck cancer.
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